Alcohol not linked to increased cardiovascular health.

heartPrevious study have correlated the light to moderate consumption of red wine to increased .

A study published in BMJ questioned those findings and determined that reducing the amount of alcoholic consumed may improve , including a reduced of coronary , lower body mass index (BMI) and blood pressure.

This study examined findings from more than 50 studies linking drinking habits and to over 260,000 people. A gene was correlated to lower over time and superior records. The  of the ‘alcohol dehydrogenase 1B’ gene is known to breakdown alcohol at a quicker pace. This rapid breakdown causes unpleasant symptoms including nausea and facial flushing, and has been found to lead to lower levels of over time.

Individuals who consumed 17 percent less alcohol per week have on average a 10 percent reduced of coronary , lower blood pressure and a lower Body Mass Index.

“These new results are critically important to our understanding of how alcohol affects . Contrary to what earlier reports have shown, it now appears that any exposure to alcohol has a negative impact upon heart health.

“For some time, have suggested that only heavy drinking was detrimental to , and that light consumption may actually be beneficial. This has led some people to drink moderately based on the belief that it would lower their of . However, what we’re seeing with this new study, which uses an investigative approach similar to a randomized clinical trial, is that reduced consumption of alcohol, even for light-to-moderate drinkers, may lead to improved ,” said co-lead author Michael Holmes, MD, PhD, assistant professor in the department of Transplant Surgery at the Perelman School of Medicine at the University of Pennsylvania.

Source

M. V. Holmes, C. E. Dale, L. Zuccolo, R. J. Silverwood, Y. Guo, Z. Ye, D. Prieto-Merino, A. Dehghan, S. Trompet, A. Wong, A. Cavadino, D. Drogan, S. Padmanabhan, S. Li, A. Yesupriya, M. Leusink, J. Sundstrom, J. A. Hubacek, H. Pikhart, D. I. Swerdlow, A. G. Panayiotou, S. A. Borinskaya, C. Finan, S. Shah, K. B. Kuchenbaecker, T. Shah, J. Engmann, L. Folkersen, P. Eriksson, F. Ricceri, O. Melander, C. Sacerdote, D. M. Gamble, S. Rayaprolu, O. A. Ross, S. McLachlan, O. Vikhireva, I. Sluijs, R. A. Scott, V. Adamkova, L. Flicker, F. M. v. Bockxmeer, C. Power, P. Marques-Vidal, T. Meade, M. G. Marmot, J. M. Ferro, S. Paulos-Pinheiro, S. E. Humphries, P. J. Talmud, I. M. Leach, N. Verweij, A. Linneberg, T. Skaaby, P. A. Doevendans, M. J. Cramer, P. v. d. Harst, O. H. Klungel, N. F. Dowling, A. F. Dominiczak, M. Kumari, A. N. Nicolaides, C. Weikert, H. Boeing, S. Ebrahim, T. R. Gaunt, J. F. Price, L. Lannfelt, A. Peasey, R. Kubinova, A. Pajak, S. Malyutina, M. I. Voevoda, A. Tamosiunas, A. H. Maitland-van der Zee, P. E. Norman, G. J. Hankey, M. M. Bergmann, A. Hofman, O. H. Franco, J. Cooper, J. Palmen, W. Spiering, P. A. d. Jong, D. Kuh, R. Hardy, A. G. Uitterlinden, M. A. Ikram, I. Ford, E. Hypponen, O. P. Almeida, N. J. Wareham, K.-T. Khaw, A. Hamsten, L. L. N. Husemoen, A. Tjonneland, J. S. Tolstrup, E. Rimm, J. W. J. Beulens, W. M. M. Verschuren, N. C. Onland-Moret, M. H. Hofker, S. G. Wannamethee, P. H. Whincup, R. Morris, A. M. Vicente, H. Watkins, M. Farrall, J. W. Jukema, J. Meschia, L. A. Cupples, S. J. Sharp, M. Fornage, C. Kooperberg, A. Z. LaCroix, J. Y. Dai, M. B. Lanktree, D. S. Siscovick, E. Jorgenson, B. Spring, J. Coresh, Y. R. Li, S. G. Buxbaum, P. J. Schreiner, R. C. Ellison, M. Y. Tsai, S. R. Patel, S. Redline, A. D. Johnson, R. C. Hoogeveen, H. Hakonarson, J. I. Rotter, E. Boerwinkle, P. I. W. d. Bakker, M. Kivimaki, F. W. Asselbergs, N. Sattar, D. A. Lawlor, J. Whittaker, G. Davey Smith, K. Mukamal, B. M. Psaty, J. G. Wilson, L. A. Lange, A. Hamidovic, A. D. Hingorani, B. G. Nordestgaard, M. Bobak, D. A. Leon, C. Langenberg, T. M. Palmer, A. P. Reiner, B. J. Keating, F. Dudbridge, J. P. Casas. Association between alcohol and : Mendelian randomisation analysis based on individual participant dataBMJ, 2014; 349 (jul10 6): g4164 DOI: 10.1136/bmj.g4164

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