BPA associated with high blood pressure.

bpaBPA also called Bisphenol A (BPA) is a common chemical, found in products such as plastic bottles and the inner lining of certain food cans.

The chemical has been associated with an adverse health impact and BPA exposure has been detected in 95% of the U.S. population.

A new study, published in the journal Hypertension, has followed up on previous work associating BPA with cardiovascular disorders such as high blood pressure and heart rate variability.

“A 5 mmHg increase in systolic blood pressure by drinking two canned beverages may cause clinically significant problems, particularly in patients with heart disease or hypertension,” said study author Dr. Yun-Chul Hong of Seoul National University College of Medicine in South Korea. “A 20 mmHg increase in systolic blood pressure doubles the risk of cardiovascular disease.”

The study consisted of a randomized crossover trial where 60 research participants were randomly provided with soy milk in either cans or glass bottles. After 2 hours, the participants’ blood pressure, heart rate variability and urinary BPA concentration were measured. Participants were asked not to eat or drink any other food for the 2 hours after drinking the soy milk, and for at least 8 hours before each trial.

The research findings revealed that drinking from cans is associated with a urinary BPA concentration increase of 1,600%. Soy milk is not associated with the ability to increase blood pressure. Systolic blood pressure increased by approximately 4.5 mmHg after the consumption of two canned beverages, compared with after the consumption of two glass-bottled beverages. No statistically significant differences in heart rate variability were observed.

The senior study author, Dr. Hong, has suggested avoiding exposure to BPA: “I suggest consumers try to eat fresh foods or glass bottle-contained foods rather than canned foods and hopefully, manufacturers will develop and use healthy alternatives to BPA for the inner lining of can containers,” he said.


Exposure to Bisphenol A from drinking canned beverage increases blood pressure, Yun-Chul Hong and Sanghyuk Bae, Hypertension, doi: 10.1161/HYPERTENSIONAHA.114.04261, published online 8 December 2014.

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