Breast Cancer associated Risk of Death linked with Smoking.

smokingThe risk of breast cancer progression and mortality in women was significantly increased by having a history of smoking or being a current smoker.

“We found that women who are current smokers or have history of smoking had a 39 percent higher rate of dying from breast cancer, even after we took into account a wide array of known including clinical, socioeconomic and ,” said Dejana Braithwaite, Ph.D, assistant professor, division of , department of epidemiology and biostatistics at the University of California, San Francisco.

The specific on breast cancer has been unclear although smoking is associated with and directly linked in several other cancers.

Braithwaite and her research team investigated the relationship between smoking and the risk of death due to breast cancer progression or non-breast cancer in a large .

They enrolled 2,265 multi- diagnosed with breast cancer between 1997 and 2000. The women were followed for an average of nine years and the results showed 164 deaths from breast cancer and 120 deaths from non . Researchers examined whether smoking affected death from breast cancer, non-breast cancer related causes and death from all causes.

Those women who had a history of smoking or who were current smokers also had a twofold increased risk for dying from non-breast cancer related causes compared with women with breast cancer who had never smoked.

In addition women who were current or past smokers and also had a HER2-negative tumor subtype had a 61 percent increased death compared with those who never smoked. Smokers with a body mass index less than 25 kg/m2 had an 83 percent increased death, and had a 47 percent increased death compared with those who never smoked.

“The implication of this research is that it is important for physicians to improve smoking cessation efforts, especially among women newly diagnosed with breast cancer, in order to improve breast cancer specific outcomes and overall health outcomes,” Braithwaite said.


American Association for Cancer Research (2010, November 9). Smoking increases risk of death in women with breast cancer, study finds.

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