Daily physical activity vital to optimal health.

dailyThe University of Missouri School of Medicine has published a new study detailing how important daily is. The study determined that reducing for a few days leads to a decrease in the function of blood vessels in the legs of young healthy subjects. This decrease in function is called vascular dysfunction.

The researchers examined the effects on the body’s blood vessels when someone transitions from high daily , defined as 10,000 or more steps per day, to low daily , less than 5,000 steps per day. The findings revealed that going from high to low levels of daily for just five days decreases the function of the inner lining of the blood vessels in the legs. Impairments in glycemic control and insulin sensitivity were also a consequence of reduced daily .

“We know the negative consequences from not engaging in can be reversed,” said Paul Fadel, associate professor of medical pharmacology and physiology, and John Thyfault, associate professor of and exercise physiology. “There is much data to indicate that at any stage of a disease, and at any time in your life, you can get active and prolong your life. However, we found that skipping just five days of causes damage to blood vessels in the legs that can take a prolonged period of time to repair.”

“Inactivity is typically going to lead to people being overweight and obese,” said Fadel. “The next step after that is insulin resistance which leads to and .”

“The best treatment is to become more active, and our lends proof to that concept,” Fadel said. “If you do not realize how harmful sitting around all day and not doing any activity is to your , this proves it.”

Source

Leryn J Reynolds, Daniel P Credeur, Seth W Holwerda, Heather J Leidy, Paul J Fadel, John P Thyfault. Acute Inactivity Impairs Glycemic Control but Not Blood Flow to Glucose Ingestion. Medicine & Science in Sports & Exercise, 2014; 1 DOI: 10.1249/MSS.0000000000000508

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