The University of Utah has published a new study specifying that the fructose-glucose mixture found in high fructose corn syrup is more toxic than sucrose or table sugar. Currently it is estimated that 13 percent to 25 percent of Americans eat a diet that includes 25 percent or more of calories in the form of added sugars; the percentage of added sugars consumed by mice in the new study. “Added sugars” are sugars added during food processing or preparation and not already naturally in food, like in a piece of fruit. Generally 44& of the added sugar is sucrose and 42% is high fructose corn syrup.
The study used a mouse model to examine the adverse impact of high fructose corn syrup. “This is the most robust study showing there is a difference between high-fructose corn syrup and table sugar at human-relevant doses,” said biology professor Wayne Potts, senior author of the study.
The researchers use a new sensitive toxicity test and it was determined that female mice on the fructose glucose diet had death rates 1.87 times higher than females on the sucrose diet. They also produced 26.4 percent fewer offspring.
Concern has arisen over high fructose syrup as a few studies have documented increased diabetes-obesity-metabolic syndrome to increased exposure of the syrup in the 1970s, when sucrose was replaced by high corn fructose in the majority of food products.
J. S. Ruff, S. A. Hugentobler, A. K. Suchy, M. M. Sosa, R. E. Tanner, M. E. Hite, L. C. Morrison, S. H. Gieng, M. K. Shigenaga, W. K. Potts. Compared to Sucrose, Previous Consumption of Fructose and Glucose Monosaccharides Reduces Survival and Fitness of Female Mice. Journal of Nutrition, 2014; DOI: 10.3945/jn.114.202531