Hepatitis vaccination campaign produces mutations.

hepatuts b
The Hepatitis B virus has mutated to cause an epidemic of “breakout” mutations of the virus in China. The mutations have been traced back to a universal public health infant vaccination campaign, the same concept that is prevalent in the United States.

Scientists at the University of North Carolina, Chapel Hill, and Chinese center for Disease Control have published their findings in the journal of virology.

The findings were based on long term surveys where the prevalence of HBV (Hepatitis B Virus) escape mutants in children rose from 6.5 percent in 1992, before the start of the universal vaccination program, to nearly 15 percent in 2005.

The adult control group who were not vaccinated with the vaccine, displayed an unchanged break out mutant rate.

The study illustrates that the virus has the ability to mutate to produce more virulent strains in response to a large scale public health risk vaccination campaign.


Bian et al. Change of Hepatitis B Large Surface Antigen Variants after 13 Years: Universal Vaccination Program in China. Journal of Virology, October 2013

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