The study authors focused their research on comparing the prevalence of cancer when the endocrine system is disrupted and they found that glyphosphate had a significant impact in human hormone-dependent breast cancer, T47D cells, but not in hormone-independent breast cancer, MDA-MB231 cells. It was determined that the estrogen element significantly induced the breast cancer cells response to Glyphosphate and acted as a mediation conductor.
The results of this study conclusively demonstrated that low and environmentally relevant concentrations of glyphosate possessed estrogenic activity. Glyphosate-based herbicides are widely used for soybean cultivation, and the results also found that there was an additive estrogenic effect between glyphosate and genistein, a phytoestrogen in soybeans.
One of the most prolific and controversial studies involving Roundup, (a Glyphosphate herbicide), and Monsanto’s genetically engineered GMO corn, (strain NK603), involved the Séralini 2012 study published in the journal of Food and Chemical Toxicology. The study produced results that were based on a long term feed study and demonstrated a wide variety of tumor development.
The most recent published study underlines the public health risks associated with Glyphosphate and their release into the environment as herbicides or contained in crop genetically engineered to be resistant to glyphosphate.
Food Chem Toxicol. 2013 Jun 10. pii: S0278-6915(13)00363-3. doi: 10.1016/j.fct.2013.05.057. [Epub ahead of print]
Glyphosate induces human breast cancer cells growth via estrogen receptors.Thongprakaisang S, Thiantanawat A, Rangkadilok N, Suriyo T, Satayavivad J.
Gilles-Eric Séralini, Emilie Clair, Robin Mesnage, Steeve Gress, Nicolas Defarge, Manuela Malatesta, Didier Hennequin, Joël Spiroux de Vendômois, “Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize,” Food and Chemical Toxicology, Available online September 19, 2012.