New England Journal of Medicine recommends that EPA delays implementation of its decision to permit use of Enlist Duo and to label Genetically Modified food.

toxic chemicalA recommendation by the New has focused on the environmental and safety hazard associated with genetically modified . The vast majority of and grown in the United States are genetically engineered and the and Drug Administration (FDA) does not require labeling of GM foods.

The International Agency for Research on (IARC) has classified glyphosate, the herbicide most widely used on GM , as a “probable human carcinogen” and classified a second herbicide, 2,4-dichlorophenoxyacetic acid (2,4-D), as a “possible human carcinogen.”

The use of genetically modified has resulted in increased herbicide resistance resulting in considerable tolerance to glyphosate (Roundup). Roundup ready account for more than 90% of the planted in the United States and glyphosate use has increased by a factor of more than 250 to 113 million kg in 2014.

The Environmental Protection Agency (EPA) has approved the use of Enlist Duo, a combination herbicide comprising glyphosate plus 2,4-D to combat resistance. It will be marketed in tandem with newly approved seeds genetically engineered to resist glyphosate, 2,4-D, and multiple other herbicides. The EPA has specified that it anticipates a 3-to-7-fold increase in 2,4-D use.

The New has offered two recommendations:

The EPA should delay implementation of its decision to permit use of Enlist Duo and the National Toxicology Program should urgently assess the toxicology of pure glyphosate, formulated glyphosate, and mixtures of glyphosate and other herbicides.

The FDA should label GM foods.


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