An Egyptian research team evaluated the safety of a genetically modified insect resistant Ajeeb corn created by incorporating the Mon 810 borer resistance gene in the best corn germplasm Ajeeb. An egyptian company is partnering with Monsanto to distribute the corn in Egypt.
Not surprisingly the researchers, after 91 days of feeding, determined numerous health side effects from the chronic ingestion of corn in rats compared to a control group. The bioassays obtained from the rats after 91 days of exposure to the corn suggests significant biochemical changes that would have a substantial health impact of exposure continued on a prolonged basis.
The findings in this study specify some of the following results:
In general, total protein and albumin concentrations from genetically modified fed rats were lower that of the control group.
A corresponding study in 2004 observed liver damage, hepatitis and cirrhosis of the liver, reduced albumin synthesis and overall decreased plasma protein.
Concentrations of ALT and ALP in rats consuming diet formulated with GM corn were higher than the values observed in the control groups. The ALT concentrations have relevance as increases in ALT concentrations may occur where there are bile stones, common liver disease, cirrhosis, hepatoxins, viral hepatitis and autoimmune liver disease .
Compared to the control group, serum total lipid content and triglyceride and cholesterol concentrations were high in rats from GM group. Significant differences were found in HDL values between the examined groups after 45 days of study,but the rats from GM group showed lower value than than the control groups.
Significant differences were observed in a similar manner in the uric acid, urea and creatinine reflecting an impact on kidney function after 91 days of exposure to GM corn. The results in this study were similar to a prior study which observed that the deficiencies in kidney function in male rats is different between animals fed NK 603 and Mon 863 genetically modified corn.
The researchers concluded that significant changes in body and organ biochemistry were observed, warned about GMO consumption and that further research is required.
Gab-Alla1, A. A., El-Shamei1, Z. S., Shatta1, A. A., Moussa2, E. A., and Rayan1, A. M. Morphological and Biochemical Changes in Male Rats Fed on Genetically Modified Corn (Ajeeb YG).Journal of American Science 2012;8(9)