Previous studies have linked obesity to a high rate of inflammation throughout the body and is normally the reaction of the body to defend against bacterial and viral invaders. Elevated chronic inflammation has been linked to an eclectic array of chronic diseases.
A Western-style diet, rich in fat and simple sugars but often poor in specific micronutrients, (folate, vitamin B12, vitamin B6, vitamin 1, vitamin E, zinc), is linked to the increased prevalence of diseases with strong immunogical and autoimmune components, including allergies, food allergies, atopic dermatitis and obesity.
“Inflammation acts as both a friend and foe, being essential in metabolic regulation, with unresolved low-grade chronic inflammation being a pathological feature of a wide range of chronic conditions including the metabolic syndrome and cardiovascular diseases,” said Prof. Anne Marie Minihane, University of East Anglia (UK). High consumption of fat and glucose may induce post-prandial inflammation (manifesting itself after the consumption of a meal), which may have consequences for the development of diabetes and cardiovascular diseases.
Anne M. Minihane, Sophie Vinoy, Wendy R. Russell, Athanasia Baka, Helen M. Roche, Kieran M. Tuohy, Jessica L. Teeling, Ellen E. Blaak, Michael Fenech, David Vauzour, Harry J. McArdle, Bas H. A. Kremer, Luc Sterkman, Katerina Vafeiadou, Massimo Massi Benedetti, Christine M. Williams, Philip C. Calder. Low-grade inflammation, diet composition and health: current research evidence and its translation. British Journal of Nutrition, 2015; 1 DOI: 10.1017/S0007114515002093