A new study, published in the issue of Rejuvenation Research, by the University of South Florida (USF) has investigated the application of a formula high in antioxidants and other natural components, which demonstratively impacted at the rate at which elderly people processed information. The supplement was tested on 105 healthy adults aged 65-85.
The nutritional supplement contained extracts from blueberries and green tea combined with vitamin D3 and amino acids, including carnosine. Blueberries, a major ingredient in the supplement, are rich in polyphenols, a type of antioxidant containing a polyphenolic, or natural phenol substructure.
“After two months, test results showed modest improvements in two measures of cognitive processing speed for those taking NT-020 compared to those taking placebo,” said Brent Small, PhD, a professor in USF’s School of Aging Studies. “Processing speed is most often affected early on in the course of cognitive aging. Successful performance in processing tasks often underlies more complex cognitive outcomes, such as memory and verbal ability.”
“The basis for the use of polyphenol-rich nutritional supplements as a moderator of age-related cognitive decline is the age-related increase in oxidative stress and inflammation,” said study co-principal investigator Paula C. Bickford, PhD, a professor in the Department of Neurosurgery and Brain Repair, USF Health Morsani College of Medicine, and senior research career scientist at the James A. Haley Veterans’ Hospital in Tampa. “Non-vitamin polyphenols are the most abundant modulators of oxidative stress and inflammation in our diet. NT-020 is 95 percent polyphenols.”
Brent Small, Kerri Rawson, Christina Martin, Sarah Eisel, Cindy D Sanberg, Cathy McEvoy, Paul Sanberg, R. Douglas Shytle, Jun Tan, Paula C Bickford. Nutraceutical Intervention Improves Older Adults’ Cognitive Functioning. Rejuvenation Research, 2013; 131017084344003 DOI: 10.1089/rej.2013.1477