Pregnancy related preeclampsia caused by lack of vitamin D.

vitdResearchers have found a new cause for preeclampsia, a life threatening condition during diagnosed by an increase in blood pressure and in the urine.

The study involved one of the largest population samples to date: 3000 mothers who did not develop preeclampsia and tracking 700 pregnant who developed preeclampsia, with a on the majority of cases, lack of vitamin D.

“For decades, vitamin D was known as a nutrient that was important only for bone health,” said lead author Lisa Bodnar, Ph.D., M.P.H., R.D., associate professor in Pitt ’s Department of Epidemiology. “Over the past 10 to 15 years, scientists have learned that vitamin D has diverse functions in the body beyond maintaining the skeleton, including actions that may be important for maintaining a healthy .”

The researchers found that vitamin D sufficiency was associated with a 40 percent reduction in risk of severe preeclampsia. But there was no relationship between vitamin D and mild preeclampsia. The overall risk of severe preeclampsia in the women sampled was 0.6 percent, regardless of vitamin D status.

“Scientists believe that severe preeclampsia and mild preeclampsia have different root causes,” said senior author Mark A. Klebanoff, M.D., M.P.H., Center for Perinatal at The Institute at Nationwide Children’s Hospital and the Department of Pediatrics at The . “Severe preeclampsia poses much higher to the mother and child, so linking it with a factor that we can easily treat, like , holds great potential.”
“If our results hold true in a modern sample of pregnant women, then further exploring the role of vitamin D in reducing the risk of preeclampsia would be warranted,” said Dr. Bodnar. “Until then, women shouldn’t automatically take vitamin D supplements during as a result of these findings.”

Source

Lisa M. Bodnar, Hyagriv N. Simhan, Janet M. Catov, James M. Roberts, Robert W. Platt, Jill C. Diesel, Mark A. Klebanoff. Maternal Vitamin D Status and the Risk of Mild and Severe Preeclampsia. Epidemiology, 2014; 1 DOI: 10.1097/EDE.0000000000000039

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