Probiotics diminish fat accumulation in the liver. Preventative measure for diabetes and obesity.

yoghurtAnother study has determined the of probiotics and has found that consuming probiotics can diminish the fat accumulation in the liver.

The findings published in the PLOS ONE journal illustrate that probiotics serve as an intervention for Non-Alcoholic a condition closely related to obesity and diabetes.

Three pobiotic strain from the Collection Nationale de Cultures de Microorganismes (CNCM) of the Pasteur Institute: Lactobacillus paracasei CNCM I-4034, breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036, were used in this study and administered to Zucker rats.

Zucker rats contain a mutation in the gene that codifies the receptor or leptin, a hormone that transmits a sensation of satiety to the . As a result of this mutation the rats are obese and among the best characterized genetic models.

The administration of probiotics led to much lower accumulation of lipids (most of them triacylglycerides) in the liver compared to the control group fed with a placebo. The rats also had a lower levels in proinflamatory (tumor-a necrosis factor, interleukin 6 and liposacarid) in the serum of rats fed with probiotics.

Source

Julio Plaza-Diaz, Carolina Gomez-Llorente, Francisco Abadia-Molina, Maria Jose Saez-Lara, Laura Campaña-Martin, Sergio Muñoz-Quezada, Fernando Romero, Angel Gil, Luis Fontana. Effects of Lactobacillus paracasei CNCM I-4034, breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036 on Hepatic Steatosis in Zucker Rats. PLoS ONE, 2014; 9 (5): e98401 DOI: 10.1371/journal.pone.0098401

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