Stinging nettle compound impacts on cancer cells.

nettlesA new study, published in the journal Nature Communications, by the University of Warwick in Britain has found that a chemical compound commonly found in stinging nettles and ants is capable of halting the production of cancer . The chemical called E-237 is derived from formic acid.

Stinging nettles have a long history of being used for medicinal use. They are commonly used to treat urinary tract infections, aches and pains, hay fever and insect bites.

Researchers combined the chemical with a compound of the metal ruthenium called JS07. The compound on its own has the capability of halting cancer progression. In combination with formate its potency is significantly increased.

“By itself, JS07 is capable of shutting down cancer but when used in combination with formate this ability is significantly increased,” says lead Prof. Peter Sadler. “As a result, lower doses would be required to cancer – reducing both the drug’s toxicity and potential side effects.”

“Cancer require a complex balance of processes to survive,” Prof. Sadler explains. “When this balance is disrupted, the cell is unable to function due to a range of process failures and eventually shuts down. The potent form of JS07 has proven to be very successful when tested on ovarian cancer .”

The cancer most affected include ovarian cancer . Ovarian cancer is the fifth leading cause of cancer in the US and it is expected that 21,290 women in the US will be diagnosed with ovarian cancer this year.

Source

Transfer hydrogenation catalysis in as a to anticancer drug design, Peter J. Sadler, et al., Nature Commun., published online 20 March 2015.

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