Breast Cancer associated Risk of Death linked with Smoking.

smokingThe risk of progression and mortality in women was significantly increased by having a history of smoking or being a current smoker.

“We found that women who are current smokers or have history of smoking had a 39 percent higher rate of dying from , even after we took into account a wide array of known prognostic factors including clinical, socioeconomic and behavioral factors,” said Dejana Braithwaite, Ph.D, assistant professor, division of cancer epidemiology, department of epidemiology and biostatistics at the University of California, San Francisco.

The specific effect of smoking on has been unclear although smoking is associated with lung cancer and directly linked in several other cancers.

Braithwaite and her team investigated the relationship between smoking and the risk of death due to progression or non- causes of death in a large group of women.

They enrolled 2,265 multi-ethnic women diagnosed with between 1997 and 2000. The women were followed for an average of nine years and the results showed 164 deaths from and 120 deaths from non causes. Researchers examined whether smoking affected death from , non- related causes and death from all causes.

Those women who had a history of smoking or who were current smokers also had a twofold increased risk for dying from non- related causes compared with women with who had never smoked.

In addition women who were current or past smokers and also had a HER2-negative tumor subtype had a 61 percent increased death compared with those who never smoked. Smokers with a body mass index less than 25 kg/m2 had an 83 percent increased death, and had a 47 percent increased death compared with those who never smoked.

“The implication of this is that it is important for physicians to improve smoking cessation efforts, especially among women newly diagnosed with , in order to improve specific outcomes and overall health outcomes,” Braithwaite said.


American Association for Cancer (2010, November 9). Smoking increases risk of death in women with , study finds.

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