Low blood sugar may have adverse effects on the heart; increasing mortality rate

lowThe journal of Diabetes has published a new study from the Lewis Katz School of Medicine at Temple University specifying the impact of hypoglycemia on the heart. Hypoglycemia is defined as having low blood sugar (when the level of sugar (glucose) in the blood is too low).

The researchers used an experimental model to investigate the change in the body’s responses to cardiovascular stress based on low blood sugar.

Healthy volunteers were exposed to experimental hypoglycemia and the volunteers were subjected to specialized testing of the cardiovascular system before and at the end of an experimental hypoglycemia period. The body’s response to changes in blood pressure and were clearly evident during periods of low blood pressure.

“These findings suggest a specific way as to how the cardiovascular system is compromised during episodes of hypoglycemia,” says Ajay D. Rao, MD, of Medicine in the Section of Endocrinology, Diabetes, and at the Lewis Katz School of Medicine at Temple University, and first author of the paper.


Ajay D. Rao, Istvan Bonyhay, Joel Dankwa, Maria Baimas-George, Lindsay Kneen, Sarah Ballatori, Roy Freeman, Gail K. Adler. Baroreflex Sensitivity Impairment During Hypoglycemia – Implications for Cardiovascular Control. Diabetes, 2015; db150871 DOI: 10.2337/db15-0871

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