Thunder God thumps Pancreatic Cancer

thundergod A little known Chinese compound is making headlines. Researchers at the University of Minnesota’s Masonic Center, have demonstrated that the thunder plant compound literally kills . The chinese plant known as the “ vine”, or “lei gong ” is an integral part of Chinese medicine and has been used to treat diverse medical conditions.

The published in the Journal of Science Translational Medicine in a paper termed “ meets the ”, stunned the scientists who have been working on the anti- properties of the compound. The new drug, called minnelide, is a modified form of the diterpenoid compound triptolide, isolated from the medicinal vine Tripterygium wilfordii. Prior studies have found triptolide to be a potent fighting agent with activity against a range of tumor types.

A highly water-soluble analog of triptolide has been synthesized by the researchers at the University of Minnesota, which is effectively converted back to the parent drug when exposed to phosphatases. Phosphatases are found in all body tissues, including blood.

The senior researcher and vice chairman of at the Center explained to the site how he was amazed by the effects of the simple plant:

“This drug is just unbelievably potent in killing ,” he said.


Sunil R. Hingorani1 and John D. Potter. Meets the . Sci Transl Med 17 October 2012:


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