Women have a higher total cancer occurrence; sitting increases risk

healthywomenA new study published in the , Biomarkers and Prevention journal has found that sitting increases the total cancer risk that women face, specifically with multiple myeloma, breast, and ovarian cancer.

The research participants consisted of 146,000 men and women, (69,260 men and 77,462 women), who were cancer-free and enrolled in the American Cancer Society Study II Nutrition Cohort.

Between 1992 and 2009, 18,555 men and 12,236 women were diagnosed with cancer. In women, sitting time was associated with risk of multiple myeloma (RR=1.65, 95% CI 1.07-2.54), invasive breast cancer (RR=1.10, 95% CI 1.00-1.21), and ovarian cancer (RR=1.43, 95% CI 1.10-1.87). The higher risk was present even after taking into account BMI, physical activity, and other factors and increased the risk by 10% in women, but not men.

The American Cancer Society guidelines for recommends reduced sitting time when possible. The research scientists recommend further research into understanding the difference between men and women and why the cancer risk is associated with specific cancers. Over the past few decades, time spent sitting has increased due to several factors, including technological advancements, like computers and video games, and changes in transportation.


Leisure-time spent sitting and site-specific cancer incidence in a large US cohort; Cancer Epidemiol Biomarkers Prev. [Epub ahead of print] Published Online First June 30, 2015; doi: 10.1158/1055-9965.EPI-15-0237

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